Conductometric determination of propranolol hydrochloride in pharmaceuticals

Conductometric determination of propranolol hydrochloride in pharmaceuticals

______________________________________________________________________________ In this paper the conductometric titration of propranolol hydrochloride in pharmaceutical formulations using silver nitrate as titrant is proposed. The method was based on the formation of an insoluble salt (AgCl(s)) between the chloride of propranolol hydrochloride molecule and Ag(I) ions of the titrant AgNO3. The e...

Conductometric Titration Method for Determination of Alfuzosin Hydrochloride and Fexofenadine Hydrochloride Using Sodium Tetraphenylborate

A simple, precise and low cost conductometric method for the determination of alfuzosin hydrochloride and fexofenadine hydrochloride in pure form and pharmaceutical formulations using sodium tetraphenylborate has been described. The method is based on the formation of ion association complex of cations coming from the cited drugs with tetraphenylborate anions and the conductance of the solution...

Fluorimetric determination of isoxsuprine hydrochloride in pharmaceuticals and biological fluids.

Two simple and highly sensitive fluorimetric methods have been developed for the determination of isoxsuprine hydrochloride in bulk, in dosage forms and in biological fluids. The first method involves the direct measurement of the native fluorescence of the drug in the concentration range 0.4-4.0 microg ml(-1), the second method is based on the oxidation of isoxsuprine HCl with cerium(IV) follo...

Spectrophotometric Determination of Fexofenadine Hydrochloride and Betamethasone in Pharmaceuticals Section 1 Spectrophometric Determination of Fexofenadine Hydrochloride in Phrmaceuticals Section Ii Spectrophotometric Determination of Betamethasone in Pharmaceuticals

Enzymatic kinetic method for determination of propranolol hydrochloride in pharmaceuticals based on its inhibitory effect on cholinesterase

Propranolol, a widely used beta-blocker, inhibits the hydrolysis reaction of enzyme cholinesterase. Measurements of the difference in rate of hydrolysis rate between uninhibited and inhibited reactions allow the development of a kinetic method for its determination. Both systems, enzyme–substrate–chromogen and enzyme–substrate–chromogen–inhibitor, were characterized through biochemical kinetic ...